Hull et al. rightly point out the special character of selection as a causal mode, but ironically they seem to force selection back into traditional causal modes by decomposing it into replication, variation, and environmental interaction. Many processes are selective, and a taxonomy of a broad range of kinds of selection may be preferable to narrowing the applicability of the term.

This paper argues against causalism about reasons in three stages. First, the paper investigates Professor Davidson's sophisticated version of the claim that we must understand reason-explanations as a kind of causal explanation to highlight the fact that this move does no explanatory work in telling us how we determine for which reasons we act. Second, the paper considers Davidson's true motivation for regarding reasons-explanations as causal which connects with his claim that reasons are causes. He advocates anomalous monism in order (...) to solve the mysterious connection problem. In assessing his proposed solution to this problem, the paper examines his 'extension reply' to the charge that his token identity theory ultimately results in epiphenomenalism. The paper argues that only a reading of this reply makes for a stable anomalous monism but for this reason Davidson's compatiblist metaphysics is unfit for the task of solving the mysteriousconnection problem. Given that reductive accounts are incompatible with the special features of reasons explanations, the paper concludes that we must reverse the orthodoxy once again and eschew causalism about reasons and reason-explanations. Finally, the paper considers a possible way of recasting our understanding of causation so that the mysterious connection problem disappears. (shrink)

Abstract Christopher Gauker has argued that a cause?effect analysis of the acquisition of communication skills in chimpanzees is adequate to describe the data reported in our work at the Language Research Center. I agree that the cause?effect approach to language function is the only viable method of analyzing language. Language must be studied as a process that functions to organize behavior between two or more individuals. However, the problem of language understanding is not addressed satisfactorily by the perspective offered by (...) Gauker. Some more recent work, particularly with the pygmy chimpanzee ?Kanzi?, is now beginning to explicate a cause?effect analysis of language comprehension. It is argued that in the young chimpanzee, as with children, language comprehension is the driving force underlying the language acquisition process. It is further argued that the transition from comprehension to production is made possible by the capacity for goal?directed observational imitation. (shrink)

Interventions that are designed to stem plagiarism do not always override the motivation of individuals to cheat and, therefore, may not diminish misconduct. To inform more effective approaches, we conducted a systematic review to clarify the psychological causes of plagiarism. This review of 83 empirical papers showed that a specific blend of circumstances may foster plagiarism: an emphasis on competition and success rather than development and cooperation coupled with impaired resilience, limited confidence, impulsive tendencies, and biased cognitions. Fortunately, whenever students (...) feel their life and studies align to their future aspirations, many of these circumstances tend to dissipate. (shrink)

Clinical primary prevention eliminates or preempts either a susceptibility or risk (synergistically a cause) in order to avoid a specific harm. Philosophically, primary prevention gets caught in the metaphysical controversy of the “hard questions” of whether it is possible to “cause not” both through a positive action (preventive act causes no harm) or no action (avoiding something causes no harm). I examine my previously proposed four-step definition of the process of prevention, discuss its limitations in light of the “hard questions,” (...) and then offer a revised five-step process definition that eliminates the “cause not” concerns by changing the goal of prevention from avoiding harm, a negative state, to achieving optimal health, a positive state. (shrink)

Continued failure to limit emissions of carbon dioxide and other greenhouse gases that are causing global climate change has brought increased attention to climate engineering technologies, which actively modify the global environment to counteract heating and climate disruptions caused by elevated greenhouse gases. Some proposed forms of CE, particularly spraying reflective particles in the upper atmosphere to reduce incoming sunlight, can cool the average temperature of the Earth rapidly and cheaply, thereby substantially reducing climate-related risks. Yet CE interventions provide (...) only imperfect corrections for the climatic and other environmental effects of elevated greenhouse gases, and carry their own environmental risks. Moreover, they may also increase other risks, by weakening political support for essential emissions reductions or providing new triggers for international conflict. These technologies thus require international governance, but also pose novel and severe challenges to current international laws and institutions. Effective governance of CE will require a capacity to make decisions regarding the conditions, if any, under which specific interventions are authorized, plus realtime operational oversight of any interventions that are conducted. Decision processes must be effectively linked with scientific research and assessment, and with institutions to manage and respond to threats of CE-related conflict. We advance preliminary suggestions to address two priority areas for early investigation: how international cooperation on early CE research can help develop shared norms that can grow robust enough to support future decision needs; and how early research and development on CE can be made to complement and encourage, rather than undermine, parallel efforts to reduce climate risks by cutting emissions. (shrink)

I shall argue in this paper that extant definitions of causality are incorrect since they do not cohere in the proper way with the concept of a cause of the universe. This lack of coherence is twofold. For some extant definitions of a cause, there are possible instances of the concept of a cause of the universe that do not satisfy the definitions. For these or other extant definitions, there are entities or occurrences that are not instances of the concept (...) of a cause of the universe but that count as causes of the universe according to the definitions. This failure of coherence between extant definitions of causality and the concept of a cause of the universe entails either that there is some other definition of a cause that is correct or that causality is indefinable. I shall suggest in the conclusion of this paper that it is more plausible to believe that causality is indefinable. (shrink)

Stuttering is one of the most well-known speech disorders, but the underlying neurological mechanisms are debated. In addition to genetic factors there are also major non-genetic contributions. It is here proposed that infection with group A beta-hemolytic streptococcus (GAS) was a major underlying cause of stuttering until the mid 1900s, when penicillin was introduced for the treatment of streptococcal infections about 1946. The main mechanism proposed is an autoimmune reaction from tonsillitis, targeting specific molecules, for example within the basal ganglia. (...) It is here also proposed that GAS infections may have continued to cause stuttering to some extent, to the present date, though more rarely. If so, early diagnosis of such cases would be of importance. Childhood cases with sudden onset of stuttering after throat infection may be particularly important to assess for possible GAS infection. The support for this hypothesis primarily comes from three lines of argument. First, medical record data from the 1930s strongly indicates that there was one type of medical event in particular that preceded the onset of childhood stuttering with unexpected frequency: diseases related to GAS throat infections. In particular, this included tonsillitis and scarlet fever, but also rheumatic fever. Rheumatic fever is a childhood autoimmune sequela of GAS infection, which was a relatively widespread medical problem until the early 1960s. Secondly, available reports of changes of the childhood prevalence of stuttering indicates striking parallels between stuttering and the incidence of rheumatic fever, with (1) decline from the early 1900s, (2) marked decline from the introduction of penicillin about 1946, and (3) reaching a more stable level in the 1960s. The correlations between the data for stuttering and for rheumatic fever after introduction of penicillin are very high, at about 0.95. Thirdly, there are established biological mechanisms linking GAS tonsillitis to immunological effects on the brain. In addition, a small number of more recent case reports have provided further support for the hypothesis linking stuttering to GAS infection. Overall, it is proposed that the available data provides strong evidence for the hypothesis that GAS infection was a major cause of stuttering until the mid 1900s. (shrink)

BackgroundThe COVID-19 pandemic has created ethical challenges for intensive care unit (ICU) professionals, potentially causing moral distress. This study explored the levels and causes of moral distress and the ethical climate in Dutch ICUs during COVID-19.MethodsAn extended version of the Measurement of Moral Distress for Healthcare Professionals (MMD-HP) and Ethical Decision Making Climate Questionnaire (EDMCQ) were online distributed among all 84 ICUs. Moral distress scores in nurses and intensivists were compared with the historical control group one year before COVID-19. (...) ResultsThree hundred forty-five nurses (70.7%), 40 intensivists (8.2%), and 103 supporting staff (21.1%) completed the survey. Moral distress levels were higher for nurses than supporting staff. Moral distress levels in intensivists did not differ significantly from those of nurses and supporting staff. “Inadequate emotional support for patients and their families” was the highest-ranked cause of moral distress for all groups of professionals. Of all factors, all professions rated the ethical climate most positively regarding the culture of mutual respect, ethical awareness and support. “Culture of not avoiding end-of-life-decisions” and “Self-reflective and empowering leadership” received the lowest mean scores. Moral distress scores during COVID-19 were significantly lower for ICU nurses (p < 0.001) and intensivists (p < 0.05) compared to one year prior.ConclusionLevels and causes of moral distress vary between ICU professionals and differ from the historical control group. Targeted interventions that address moral distress during a crisis are desirable to improve the mental health and retention of ICU professionals and the quality of patient care. (shrink)

What does it mean to ‘calculate’—today? The pause introduced by the dash in this question marks the inescapable necessity of historicizing the problem of calculation. In his provocative essay, ‘Toward a Critique of the Ineffectual: Heidegger’s Reading of Aristotle and the Construction of an Action without Ends’, Dimitris Vardoulakis proposes a philosophical and political programme in order to counter the negative effects of ‘Heidegger’s mistake’ (the conflation of causality and instrumentality through a mistranslation of Aristotle) that has led to the (...) theoretical fetishization of the ‘ineffectual’ (action without ends) in continental philosophy. In his conclusion, Vardoulakis advocates for a return to a politics and ethics of practical judgment that avoids the twin pitfalls of asserting either the impossibility or the absolute possibility of calculation. As he puts it, we need to acknowledge today ‘the exigency to calculate in the face of the provisional ends of instrumentality, or to perform the judgment that the Greeks called phronesis’ [2022: 244]. This is why we should keep in mind that Heidegger’s critique of technology in the 1950s was articulated in the context of the early Cold War, atomic warfare, and the rise of cybernetics. But, as many have recently argued, in the age of so-called ‘Big Data’, neoliberal rationality has increasingly replaced the epistemology of ‘causality’ with epistemologies of ‘correlation’: the algorithmic calculation of probabilistic relations between clusters of variables (based on information harvested by digital technologies designed for the total surveillance of human life). As Chris Anderson notoriously announced in his 2008 editorial, ‘The End of Theory’, ‘correlation supersedes causation, and science can advance even without coherent models, unified theories, or really any mechanistic explanation at all’. He calls this epistemology ‘dimensionally agnostic statistics’ (the amount of data available can no longer be visualized in its totality). This worldview, however, functions as a basic attack on one of the fundamental (and still often repeated) ground-truths of modern science: correlation is not causation. As Anderson puts it: ‘There is now a better way. Petabytes allow us to say: “Correlation is enough”’. In other words, the stakes of Vardoulakis’s argument must be tested against the rise of this neoliberal elimination of causality from corporate epistemologies that has led to an inversion of the terms of the Heideggerian critique of technology: as it turns out, technology has produced an ideology of pure instrumentality without causation. Today, there are only ends without causes. (shrink)

In section 96 of Reasons and Persons, Derek Parfit offers his now familiar tripartite distinction among candidates for ‘what matters’: (1) Relation R with its normal cause; (2) R with any reliable cause; (3) R with any cause. He defends option (3). This paper tries to show that there is important ambiguity in this distinction and in Parfit's defence of his position. There is something strange about Parfit's way of dividing up the territory: I argue that those who have followed (...) him in viewing the choice among (1)–(3) as the (or an) important question in thinking about ‘what matters’ are mistaken, and that they bypass what seems to be a more important, even crucial, set of options and considerations. I am less concerned with what he does say than with what he ought to say, given his intuitions and arguments, and the general framework within which he is working. And I am particularly concerned to show that whether or not I am correct about what he is doing with his tripartite distinction, it is a distinction with which we should not be particularly concerned in the analysis either of what matters or of psychological continuity. (shrink)

According to a classical teaching, God is not really related to creatures even by virtue of creating them. Some have objected that this teaching makes unintelligible the claim that God causally accounts for the universe, since God would be the same whether the universe existed or not. I defend the classical teaching, showing how the doctrine is implied by a popular cosmological argument, showing that the objection to it would also rule out libertarian agent causality, and showing that the objection (...) rests on an account of causality and sufficient reason that we have good reason to reject. (Published Online January 15 2007). (shrink)

IN THE DISCUSSION on education in the Republic, Socrates lays down the principles which those who speak about the gods must follow if they want to avoid the errors of traditional mythology. The first typos of this rational theology is this: "God is the cause, not of all things, but only of the good." For "God, being good, cannot be responsible for everything happening in our life, as is commonly believed, but only for a small part. For we have a (...) far smaller share of good than of evil, and while God must be held to be the sole cause of good, we must look for some other factors than God as cause of the evil." Rightly celebrated, this passage has set the agenda for ages of reflection in Western thought on the cause of evil. In contrast to traditional mythology where the gods are seen as the origin of both good and evil--as Homer says, "Zeus has two jars standing on the floor of his palace, full of fates, good in one and evil in the other"--the divinity is now freed of all responsibility for evil. God, who is entirely good, can only be the cause of well-being. If this answer sets God free of all responsibility for evil, it seems to be at the cost of limiting God's power: for God is no longer responsible for "most things in human life," since most of them are evil. What, then, may be the cause or causes of evil? Do bad things have a cause? Or do they just happen? Plato's formulation seems to suggest that he favours a dualistic solution to the problem of evil: God is the cause of all good, but for evil we have to find other causes. What could those causes be: matter, cosmic necessity, an evil soul? Various answers of this type were developed in later Platonism and in later mythological philosophies. Without denying that Plato often uses a dualistic discourse and uses elements of it in his cosmology, I do think that Plato had something different in mind. After all, he was not primarily interested in the problem of theodicy. For in this passage of the Republic, he is not concerned with the problem of evil in the universe as a whole, which is really the theodicy question, but with evil in "human life," that is, evil insofar as human beings experience it and suffer from it: the fact that we are not at all living well but are instead miserable and unhappy. (shrink)

Most writers on causation have distinguished causal relations or natural necessities from mere correlations or accidental generalizations. I shall assume that this is a valid distinction. However, a "Dogma" of empiricism has been that natural necessity does not amount to logical necessity and that causes are contingently related to effects. In this paper I shall argue that this Dogma is mistaken.

Background: Dementia is one the major problems of aging societies, and, novel and effective non-drug therapies are required as interventions in the oldest-old to prevent cognitive decline.Objective: This study aims to examine the efficacy and safety of reminiscence using immersive virtual reality focusing on anxiety that often appears with cognitive decline. The secondary objective is to reveal the preference for VR image types for reminiscence: live-action or computer graphics.Methods: This was a pilot, open-label, and randomized crossover study which was conducted (...) on January 2020 at a single nursing home. The subjects were randomly divided into two groups in equal numbers, and they alternately viewed two types of VR images themed on the mid- to late Showa era in Japan. In group A, the CG images were viewed first, and then the LA images were viewed. In group B, the images were viewed in the opposite order. Before VR viewing, subjects responded to Mini-Mental State Examination Japanese version and State-Trait Anxiety Inventory Japanese version. After viewing the first and second VR, subjects responded to STAI and the numerical rating scale for satisfaction and side effects.Results: Ten subjects participated in this study. The values of analyses are presented in the mean. The age was 87.1 years, and the MMSE was 28.5. The total STAI score before VR viewing was 36.1, but it significantly decreased to 26.8 after the first VR viewing, and further decreased to 23.4 after the second VR viewing. The NRS score for satisfaction tended to be higher after viewing LA in group A vs. 8.6, P = 0.0993), while in group B, the score after CG was slightly lower than that after LA. There were no serious side effects.Conclusions: This study suggests that iVR reminiscence can reduce anxiety in the oldest-old without causing serious side effects. Furthermore, the impacts might be better with LA images. (shrink)

The paper argues for a pragmatic account of genetic explanation. This is to say that when a disease or other trait is termed genetic, the reasons for singling out genes as causes over other, also necessary, genetic and nongenetic conditions are not wholly theoretical but include pragmatic dimensions. Whether the explanation is the presence of a trait in an individual or differences in a trait among individuals, genetic explanations are context-dependent in three ways: they are relative to a causal background (...) of genetic and nongenetic factors; they are relative to a population; and they are relative to the present state of knowledge. Criteria like causal priority, nonstandardness, and causal efficacy that purport to distinguish objectively between genetic causes and nongenetic conditions either incorporate pragmatic elements or fail for other reasons. When the pragmatic dimensions of genetic explanations are recognized, we come to understand the current phenomenon of geneticization to be a reflection of increased technological capacities to manipulate genes in the laboratory, and potentially the clinic, rather than theoretical progress in understanding how diseases and other traits arise. This calls into question the value of the search for theoretical definitions of designations like genetic disease or genetic susceptibility as directives for action. (shrink)

The aim of this paper will be to try and show why there could not be any acceptable counter-stipulation-example to this analytic truth. The overall strategy will be to articulate the conceptual centrality of this analytic truth by showing that a change in it will cause absurdities to break out in certain neighboring concepts with which the concept of cause has logical liaisons, such as action, possibility, intention, deliberation, memory, responsibility, and punishment: and when we try to protect ourselves from (...) these absurdities by altering these latter concepts as well, we will have twisted our concept of causality, along with these other concepts, out of recognition. In other words, it will be argued that to give up this analytic truth will require such a drastic overhauling of the basic concepts of our conceptual system that they will not be a recognizable analog of their former self. Obviously, I cannot give any precise criterion for just when an altered concept ceases to be a permissible analog of its former self. While there is room for disagreement about these matters, we can reach agreement upon the logical connections between the concept of causality and these other neighboring concepts, so that we can determine what changes must be made in the latter so as to accommodate a change in the former. Whether we then wish to say that these changes are so extensive that these concepts are not permissible analogs of their former selves is of secondary importance. However, I do believe that it can be shown that the extended concept of causality which permits a cause to be later than its effect requires such a drastic change in neighboring concepts that there will be little room for disagreement as to whether it is a legitimate analog to the original concept of causality. (shrink)

T. A. Cavanaugh defends double-effect reasoning (DER), also known as the principle of double effect. DER plays a role in anti-consequentialist ethics (such as deontology), in hard cases in which one cannot realize a good without also causing a foreseen, but not intended, bad effect (for example, killing non-combatants when bombing a military target). This study is the first book-length account of the history and issues surrounding this controversial approach to hard cases. It will be indispensable in theoretical ethics, (...) applied ethics (especially medical and military), and moral theology. It will also interest legal and public policy scholars. (shrink)

Background: Nursing students on clinical placements as part of their professional training are routinely faced with situations involving ethical conflicts. The initial act of perceiving a situation as causing an ethical dilemma is the result of both the students’ personal values, drawn from their culture and families, and of the professional knowledge and values that they have acquired through training and experience. Objectives: Nursing students’ experiences on clinical placements in primary care settings were investigated in order to identify situations (...) that they perceived as involving ethical conflict and describe the elements they took into consideration during their decision-making processes in these situations. Methods: The research design was qualitative descriptive case study. Around 50 students from three different intakes to a nursing degree answered a questionnaire and discussed it in focus groups. Ethical considerations: The study was designed in accordance with the principles guiding research with human beings and was approved by the Human Research Ethics Committee. Results: Synthesised into two principal axes: (a) ethical conflicts in primary care, linked with the domains of working processes, professional nursing ethics and human and social rights and (b) students’ decision-making processes – realisation, reflection and intervention. Conclusion: The student nurses saw themselves both as actors and spectators in situations involving ethical problems and demanding moral deliberation, demonstrating the ability to base their arguments soundly. They tended to emphasise the possibilities offered by dialogue and that different ethical values must be respected to find fair solutions to ethical problems. (shrink)

Contemporary debates on divine action tend to focus on finding a space in nature where there would be no natural causes, where nature offers indeterminacy, openness, and potentiality, to place God’s action. These places are found through the natural sciences, in particular quantum mechanics. God’s action is then located in those ontological ”causal-gaps’ offered by certain interpretations of quantum mechanics. In this view, God would determine what is left underdetermined in nature without disrupting the laws of nature. These contemporary proposals (...) evidence at least two unexamined assumptions, which frame the discussion in such a way that they portray God as acting as a secondary cause or a ”cause among causes’. God is somewhat required to act within these ”gaps’, binding God to the laws of nature, and placing God’s action at the level of secondary causes. I suggest that understanding God’s action, following Thomas Aquinas, in terms of primary and secondary causation could help dissolve this difficulty. Aquinas moves away from this objection by suggesting to speak of an analogical notion of cause, allowing for an analogical understanding of God’s causality in nature. With a radically different understanding of the interplay between secondary causes and God, Aquinas manages to avoid conceiving God as a cause among causes, keeping the distinctive transcendent character of God’s causality safe from objections. (shrink)

Biological fitness is a foundational concept in the theory of natural selection. Natural selection is often defined in terms of fitness differences as “any consistent difference in fitness (i.e., survival and reproduction) among phenotypically different biological entities” (Futuyma 1998, 349). And in Lewontin’s (1970) classic articulation of the theory of natural selection, he lists fitness differences as one of the necessary conditions for evolution by natural selection to occur. Despite this foundational position of fitness, there remains much debate over the (...) nature of fitness, especially whether fitness differences can truly be said to cause evolutionary change. In recent years these debates have crystalized into two camps: (1) causalists, who see fitness differences as being one of the causes of evolutionary change, and (2) statisticalists, who deny the causal efficacy of fitness and instead hold that “fitness is a mere statistical, noncausal property of trait types” (Walsh 2010, 148). (shrink)

The epistemic theory of causality maintains that causality is an epistemic relation, so that causality is taken to be a feature of the way an agent represents the world rather than an agent-independent or non-epistemological feature of the world. The objective of this essay is to cause problems for the epistemic theory of causality. This is not because I think that the epistemic theory is incorrect. In fact, I spend some time arguing in favour of the epistemic theory of causality. (...) Instead, this essay should be regarded as something like an exercise in stress testing. The hope is that by causing problems for a particular version of the epistemic theory, the result will be a more robust version of that theory. My gripe is with a particular version of the epistemic theory of causality, a version that is articulated with the help of objective Bayesianism. At first sight, objective Bayesianism looks like a plausible theory of rational belief. However, I argue that it is committed to a certain theory of evidence, a theory of evidence that recent work in epistemology has shown to be incorrect. In particular, objective Bayesianism maintains that evidence is perfectly accessible in a certain sense. But evidence just is not so perfectly accessible, according to recent developments in epistemology. However, this is not the end of the line for the epistemic theory of causality. Instead, I propose an epistemic theory of causality that dispenses with the assumption that evidence is perfectly accessible in the relevant sense. (shrink)

It was Marx who first formulated what later became known as the idea of the working class as an ‘emancipatory subject’. In his view, the workers alone were able to orchestrate a revolution that would put an end to capitalism. The purpose of this paper is to show that this line of thought is ideological by Marx’s own standards, and that while the working class never constituted the coherent political subject that Marx wanted it to become, its non-existence produced distinct (...) theoretical effects not just in his work, but also in the Marxist tradition. After a brief discussion of the different criticisms of the idea of the working class as emancipatory subject put forward by Hardt, Negri, Laclau, and Mouffe, an attempt is made to demonstrate how Althusser’s structural approach is better suited to formulate an alternative to the traditional view. Finally it is argued that this alternative stays within a general Marxist framework. (shrink)

Emotion Review, Volume 14, Issue 3, Page 167-181, July 2022. A growing cadre of influential scholars has converged on a circumscribed definition of empathy as restricted only to feeling the same emotion that one perceives another is feeling. We argue that this restrictive isomorphic matching definition is deeply problematic because it deviates dramatically from traditional conceptualizations of empathy and unmoors the construct from generations of scientific research and clinical practice; insistence on an isomorphic form undercuts much of the functional value (...) of empathy from multiple perspectives of analysis; and combining the opposing concepts of isomorphic matching and self-other awareness implicitly requires motivational content, causing the RIM definition to implicitly require the kind of non-matching emotional content that it explicitly seeks to exclude. (shrink)

Dandruff is a common scalp condition, which frequently causes psychological distress in those affected. Dandruff is considered to be caused by an interplay of several factors. However, the pathogenesis of dandruff remains under‐investigated, especially with respect to the contribution of the hair follicle. As the hair follicle exhibits unique immune‐modulatory properties, including the creation of an immunoinhibitory, immune‐privileged milieu, we propose a novel hypothesis taking into account the role of the hair follicle. We hypothesize that the changes and imbalance of (...) yeast and bacterial species, along with increasing proinflammatory sebum by‐products, leads to the activation of immune response and inflammation. Hair follicle keratinocytes may then detect these changes in scalp microbiota resulting in the recruitment of leukocytes to the inflammation site. These changes in the scalp skin immune‐microenvironment may impact hair follicle immune privilege status, which opens new avenues into exploring the role of the hair follicle in dandruff pathogenesis. Also see the video abstract here: https://youtu.be/mEZEznCYtNs. (shrink)

This paper reviews and extends ideas of eukaryotization by endosymbiosis. These ideas are put within an historical context of processes that may have led up to eukaryotization and those that seem to have resulted from this process. Our starting point for considering the emergence and development of life as an organized system of chemical reactions should in the first place be in accordance with thermodynamic principles and hence should, as far as possible, be derived from these principles. One trend to (...) be observed is the ever-increasing complexity resulting in several layers of compartmentalization of the reaction system, either spatial (of which the eukaryotic cell is an example), or functional (as in the gradually deepening distinction between metabolic, enzymatic and information-storing functions within the cell). One of the causes of this complexification of living systems will have been the changes in environmental conditions, particularly the geochemical impoverishment of the biosphere during geological history, partly brought about by living systems themselves, and partly by the trend towards increasing efficiency and specificity of the reactions that occur. (shrink)

Loneliness has been reframed from a ‘social problem of old age’ into a major public health problem. This transformation has been generated by findings from observational studies of a relationship between loneliness and a range of negative health outcomes including dementia. From a public health perspective, key to evaluating the relationship between loneliness and dementia is examining how studies define and measure loneliness, the exposure variable, and dementia the outcome. If we are not consistently measuring these then building a body (...) of evidence for the negative health outcomes of loneliness is problematic. Three key criteria had to meet for studies to be included in our analysis. To test the proposition that loneliness is a cause of dementia we only included longitudinal studies. For inclusion studies had to measure loneliness at baseline, have samples free of dementia and assess dementia at follow up. We identified 11 papers published between 2000 and 2018 that meet these criteria. These studies included seven different countries and only one was specifically focused upon dementia: all other studies were cohort studies focused upon ageing and health and wellbeing. There was extensive heterogeneity in how studies measured loneliness and dementia and in the use of co-variates. Loneliness was measured by either self-rating scales or scales. Dementia was assessed by clinical tests, diagnostic/screening tools, cognitive function tests, and self-reported doctor diagnosis. Substantial variation in loneliness prevalence and dementia incidence. Six studies did not report a statistically significant relationship between loneliness and dementia. Significant excess risk of dementia among those who were lonely ranged from 15% to 64%. None of these studies are directly comparable as four different loneliness and dementia measures were used. We suggest that the evidence to support a relationship between loneliness and dementia is inconclusive largely because of methodological limitations of existing studies. If we wish to develop this evidence base, then using a consistent set of loneliness and dementia outcome measures in major longitudinal studies would be of benefit. (shrink)

Two studies demonstrate that a dispositional proneness to disgust (“disgust sensitivity”) is associated with intuitive disapproval of gay people. Study 1 was based on previous research showing that people are more likely to describe a behavior as intentional when they see it as morally wrong (see Knobe, 2006, for a review). As predicted, the more disgust sensitive participants were, the more likely they were to describe an agent whose behavior had the side effect of causing gay men to kiss (...) in public as having intentionally encouraged gay men to kiss publicly— even though most participants did not explicitly think it wrong to encourage gay men to kiss in public. No such effect occurred when subjects were asked about heterosexual kissing. Study 2 used the Implicit Association Test (IAT; Nosek, Banaji, & Greenwald, 2006) as a dependent measure. The more disgust sensitive participants were, the more they showed.. (shrink)

Pier Paolo Pasolini (1922–1975) was a versatile Italian artist, writer, poet, screenwriter, playwright, actor and film director. History also remembers him as a public intellectual, philosopher, cr...

Advocates of the counterfactual approach to causal inference argue that race is not a cause, and this despite the fact that it is commonly treated as such by scientists in many disciplines. I object that their argument is unsound since two of its premises are false. I also sketch an argument to the effect that racial discrimination cannot be explained unless one assumes race to be a cause.

What effect does witnessing other students cheat have on one's own cheating behavior? What roles do moral attitudes and neutralizing attitudes (justifications for behavior) play when deciding to cheat? The present research proposes a model of academic dishonesty which takes into account each of these variables. Findings from experimental (vignette) and survey methods determined that seeing others cheat increases cheating behavior by causing students to judge the behavior less morally reprehensible, not by making rationalization easier. Witnessing cheating also has (...) unique effects, controlling for other variables. (shrink)

As the world held its breath for news surrounding COVID-19 and hunkered down amidst stay-at-home orders, medical students across the U.S. wondered if they would be called to serve on the front lines of the pandemic. Medical school administrators faced the challenge of protecting learners while also minimizing harm to their medical education. This balancing act raised critical questions in medical education as institutions reacted to changing guidelines. COVID-19 has punctuated already contentious areas of medical education and has forced institutions (...) and organizations to take quick action. From the perspectives of a recent medical school graduate and current resident and a practicing clinician-educator, we examine the pandemic’s impact on undergraduate medical education through an ethical lens. First, we explore the value of medical education, what drives this value, and how COVID-19 may alter it. We next consider student choice and how shifts toward utilitarianism in healthcare during a pandemic may affect learning and career exploration. Then, we inquire how access to technology may impact the experience of medical students from diverse backgrounds and varied institutions during a rapid shift to socially distanced learning. We identify vulnerabilities for students at several phases of the journey: premedical, preclinical, clinical, and preparation for residency. Finally, we address the hidden curriculum of COVID-19, its potential erosion of empathy among current medical students, and possible long-term consequences for future physicians and patients. (shrink)

Does a person's liability to attack during a war depend on the nature of their individual causal contribution to the (unjust) threat posed? If so, how? The recent literature on the ethics of war has become increasingly focused on questions of this kind. According to some views on these matters, your liability hinges on the extent of your causal contribution: the larger your contribution to an unjust threat, the larger the amount of harm that we can impose on you in (...) order to avert the threat. Some philosophers have suggested that we can ground a quite general principle of civilian immunity on this basis. But, do causal contributions really come in degrees? Can we make sense of a graded notion of causal contribution that can be relevant to debates about liability in war? I argue there is good reason to be sceptical. The appearance that causal contributions come in degrees is just an illusion that can be explained away. (shrink)

In _Discrimination Against the Dying_, Philip Reed argues, among other things, that ‘right to die laws (euthanasia and assisted suicide) also exhibit terminalism when they restrict eligibility to the terminally ill’. 1 Additionally, he suggests ‘the availability of the option of assisted death only for the terminally ill negatively influences the terminally ill who wish to live by causing them to doubt their choice’. 1 I argue that on scrutiny, neither of these two points hold. First, we routinely limit (...) a course of treatment to only those for whom we believe the treatment might provide a benefit. Typically, we do not think hastening death provides benefit when an individual is not experiencing a terminal illness. Thus, I conclude, either all treatments are discriminatory, or medical aid in dying is not. Second, I argue that permitting individuals to refuse or remove life sustaining care may very well cause... (shrink)